Each tablet contains: Nifedipine U.S.P 20 mg.
Nifedipine Retard Tablets: Depin-E Retard is a slow release formulation of Nifedipine. It provides sustained levels of Nifedipine for constant therapeutic effects. Nifedipine is a potent vasodilator and antianginal drug which belongs to the calcium channel blockers. Nifedipine is a dihydropyridine derivative. It is chemically designated as 1,4 dihydro-2, 6-dimethyl-4(2-nitrophenyl) pyridine-3, 5-dicarboxylate.
Pharmacology: Mechanism of Action: Nifedipine has a vasodilator effect. It produces peripheral arteriolar dilatation and consequent reduction in peripheral vascular resistance and afterload. Nifedipine produces reduction in both systolic and diastolic blood pressure. It also dilates coronary arteries and improves coronary circulation.
Depin-E Retard is indicated for the treatment of hypertension and angina pectoris.
1 tablet of Depin-E Retard twice in a day. If required, the dose may be increased to 2 tablets twice in a day as directed by the physician.
Known hypersensitivity to Nifedipine.
Since occasion patients may develop hypertension with Nifedipine, careful observation and monitoring of blood pressure is recommended in patients at the time of initial titration and higher dosage adjustment especially in patients who are on other anti-hypertensive drug. There are no controlled studies about the use of Nifedipine in pregnancy and it should be used in pregnancy only when the potential benefits justifies its use.
Depin-E Retard is well tolerated in most of the patients. Side effects are generally not serious and do not require discontinuation of therapy. Most of the side effect are expected consequences of the vasodilator effect of Nifedipine. The side effects seen with Depin-E Retard are dizziness, light headedness, giddiness, flushing, headache, weakness, nausea, peripheral oedema, palpitations and nasal stuffiness. Transient hypotension or rarely increase in angina may occur. Nifedipine may increase plasma digoxin levels and may cause glucose intolerance.
Store below 25°C, protect from light.
C08CA05 - nifedipine ; Belongs to the class of dihydropyridine derivative selective calcium-channel blockers with mainly vascular effects. Used in the treatment of cardiovascular diseases.
Depin-E Retard tab 20 mg
10 × 10's
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